In the operating room, leaning over his patient’s partially amputated leg and holding a file-like knife, Nedret slashes at some bloody muscle. He needs to cut it so that it fits under the skin flap that will cover the patient’s stump. The patient lows softly, like a cow. Then Nedret prepares to shorten the leg bone. He attaches two scissors-like hemostat clamps to the top edge of the skin flap and hands one of them to Ilijaz to hold steady. With his left hand, Nedret grips the protruding leg bone, the tibia, with a tool that looks like a giant pair of pliers. His right hand lifts azhaga, a p-shaped saw. As he saws, the patient moans and bucks, and Ilijaz and the others holding him rock back and forth. zithromax dosing for pediatric patients In an effort to capitalize on the anesthetic properties of PCP while minimizing its psychological effects, scientists synthesized at least 200 derivatives of the chemical and found one—double ring-shaped C13H16ClNO—that worked best on laboratory animals. Named keta mine in the late 1960s, it soon became clear this PCP relative also caused dramatic psychic reactions on emergence from anesthesia. Patients experienced everything from vivid imagery and pleasant dreams to delirium and disturbing hallucinations.Again, the drug traveled to the street. This time it stayed in the operating room, too, for several specific uses—trauma victims with blood loss, patients suffering septic shock from infection, and those at poor risk for other forms of anesthesia.